Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10675049 | 0.86 | KMT2A (0.43) | ALDH1A1L3MBTL1LMNAKDM4EGAA | |
| SCHEMBL10681828 | 0.85 | CDC7 (0.47) | ALDH1A1L3MBTL1LMNAKDM4EGAA | |
| SCHEMBL10679859 | 0.84 | CTNNB1 (0.43) | ALDH1A1L3MBTL1LMNAKDM4EGAA | |
| SCHEMBL10676766 | 0.81 | CDC7 (0.42) | ALDH1A1L3MBTL1LMNAKDM4EGAA | |
| SCHEMBL10684544 | 0.80 | CDK5 (0.54) | ALDH1A1L3MBTL1LMNAMAPTCDK5 | |
| SCHEMBL7384310 | 0.78 | PDE3B (0.52) | ALDH1A1LMNAMAPTKDM4EGAA | |
| SCHEMBL10682007 | 0.77 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1LMNAMAPTCDK5 | |
| SCHEMBL10676194 | 0.77 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1LMNAMAPTCDK5 | |
| SCHEMBL10682164 | 0.76 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1LMNAMAPTCDK5 | |
| SCHEMBL10680104 | 0.75 | KMT2A (0.44) | ALDH1A1L3MBTL1LMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769380-A | Cardiotonic 5-benzoyl-1,2-dihydro-2-oxo-3-pyridinecarboxylates | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-09-06 | — | — | US | disclosed |