Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10675049 | 0.89 | KMT2A (0.43) | CDC7RAB9AKMT2AKDM4EOPRK1 | |
| SCHEMBL10676766 | 0.86 | CDC7 (0.42) | CDC7RAB9AKMT2AKDM4EOPRK1 | |
| SCHEMBL10679859 | 0.85 | CTNNB1 (0.43) | RAB9AKMT2AKDM4EOPRK1GAA | |
| SCHEMBL10680545 | 0.85 | ALDH1A1 (0.50) | KDM4EGAAALDH1A1HPGDTSHR | |
| SCHEMBL7384310 | 0.81 | PDE3B (0.52) | RAB9AKMT2AKDM4EOPRK1GAA | |
| SCHEMBL10678289 | 0.79 | CDC7 (0.56) | CDC7KMT2A | |
| SCHEMBL10680104 | 0.78 | KMT2A (0.44) | CDC7RAB9AKMT2AKDM4EOPRK1 | |
| SCHEMBL10684504 | 0.75 | CDC7 (0.40) | CDC7KDM4ETSHRSMN1; SMN2NAPRT | |
| SCHEMBL10676837 | 0.74 | CDC7 (0.42) | CDC7RAB9AGAAALDH1A1HPGD | |
| SCHEMBL10681929 | 0.74 | CDC7 (0.42) | CDC7RAB9AKMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769380-A | Cardiotonic 5-benzoyl-1,2-dihydro-2-oxo-3-pyridinecarboxylates | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-09-06 | — | — | US | disclosed |