Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7544500 | 0.78 | MAPK1 (0.41) | ALDH1A1SMN1; SMN2L3MBTL1GAAMEN1 | |
| SCHEMBL19808057 | 0.76 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2L3MBTL1HTTGAA | |
| SCHEMBL19762749 | 0.75 | — | — | |
| SCHEMBL25143338 | 0.73 | — | — | |
| SCHEMBL4573217 | 0.73 | MEN1 (0.48) | ALDH1A1SMN1; SMN2L3MBTL1HTTGAA | |
| SCHEMBL14860821 | 0.72 | KCNH2 (0.37) | ALDH1A1SMN1; SMN2L3MBTL1HTTGAA | |
| SCHEMBL4360008 | 0.72 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2L3MBTL1HTTGAA | |
| SCHEMBL8231074 | 0.71 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2L3MBTL1HTTGAA | |
| SCHEMBL20740304 | 0.70 | MET (0.44) | ALDH1A1SMN1; SMN2L3MBTL1HTTGAA | |
| SCHEMBL17550764 | 0.70 | OPRM1 (0.52) | ALDH1A1SMN1; SMN2L3MBTL1HTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732977-A | BACTERICIDES | BRISTOL MYERS COMPANY (US) | 1988-03-22 | — | — | US | disclosed |