Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537847 | 0.78 | KMT2A (0.33) | KMT2AALDH1A1GPR139 | |
| SCHEMBL10680972 | 0.78 | ALDH1A1 (0.41) | MAPK1L3MBTL1OPRM1OPRK1KMT2A | |
| Tibenzate SCHEMBL2110094 | 0.75 | IDO1 (0.52) | L3MBTL1KMT2ALMNAHDAC1SMN1; SMN2 | |
| SCHEMBL15570529 | 0.73 | SMN1; SMN2 (0.59) | MAPK1L3MBTL1KMT2ALMNAHPGD | |
| SCHEMBL9735929 | 0.72 | OPRM1 (0.44) | MAPK1L3MBTL1OPRM1OPRK1JAK2 | |
| SCHEMBL28460668 | 0.71 | IDO1 (0.52) | L3MBTL1KMT2ALMNAHPGDHDAC1 | |
| SCHEMBL1479171 | 0.71 | NAPRT (0.53) | KMT2ALMNASMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL7547678 | 0.71 | HPGDS (0.40) | MAPK1KMT2AHDAC1HDAC3HDAC4 | |
| SCHEMBL5702311 | 0.69 | ALDH1A1 (0.52) | L3MBTL1KMT2ALMNAHPGDHDAC1 | |
| SCHEMBL28463445 | 0.69 | IDO1 (0.58) | L3MBTL1KMT2ALMNARAB9AFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6468995-B1 | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-10-22 | — | — | US | disclosed |
| EP-0667868-B1 | CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-05-15 | — | — | EP | disclosed |
| US-20010056089-A1 | Novel crystal of cephalosporin compound | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-12-27 | — | — | US | disclosed |
| US-20010007903-A1 | NOVEL CRYSTAL OF CEPHALOSPORIN COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-07-12 | — | — | US | disclosed |
| EP-0780393-A1 | NOVEL CRYSTAL OF CEPHALOSPORIN COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |
| CN-1116425-A | New cephem compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-02-07 | — | — | CN | disclosed |
| EP-0667868-A1 | NEW CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-08-23 | — | — | EP | disclosed |
| WO-1995007283-A1 | NEW CEPHEM COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010056089-A1 | Novel crystal of cephalosporin compound | CEP170, CXXC4, DAO | MAPK1 2697/4885L3MBTL1 4138/4885OPRM1 3136/4885 |
| US-20010007903-A1 | NOVEL CRYSTAL OF CEPHALOSPORIN COMPOUND | CEP170, CXXC4, DAO | MAPK1 2697/4885L3MBTL1 4138/4885OPRM1 3136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.