Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10680362 | 0.86 | SRD5A2 (0.48) | ALDH1A1MAPTTDP1MAPK1NPSR1 | |
| SCHEMBL10680367 | 0.86 | GAA (0.43) | ALDH1A1MAPTTDP1MAPK1NPSR1 | |
| SCHEMBL10684242 | 0.85 | GAA (0.49) | ALDH1A1MAPTTDP1MAPK1NPSR1 | |
| SCHEMBL10680708 | 0.85 | MAPT (0.49) | ALDH1A1MAPTTDP1MAPK1NPSR1 | |
| SCHEMBL7382511 | 0.83 | PDE3B (0.43) | ALDH1A1MAPTTDP1MAPK1NPSR1 | |
| SCHEMBL10680841 | 0.81 | MAPK1 (0.45) | ALDH1A1MAPTTDP1MAPK1NPSR1 | |
| SCHEMBL10682046 | 0.80 | MAPT (0.48) | ALDH1A1MAPTMAPK1NPSR1KDM4E | |
| SCHEMBL10681150 | 0.74 | UCHL1 (0.50) | ALDH1A1MAPTTDP1KDM4ESRD5A2 | |
| SCHEMBL10681969 | 0.74 | MAPT (0.47) | ALDH1A1MAPTTDP1MAPK1SRD5A2 | |
| SCHEMBL10676837 | 0.73 | CDC7 (0.42) | ALDH1A1MAPTMAPK1SRD5A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769380-A | Cardiotonic 5-benzoyl-1,2-dihydro-2-oxo-3-pyridinecarboxylates | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-09-06 | — | — | US | disclosed |