Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10675823 | 0.90 | CDC7 (0.38) | MAPTALDH1A1L3MBTL1GAALMNA | |
| SCHEMBL10677717 | 0.87 | ALDH1A1 (0.44) | MAPTALDH1A1L3MBTL1GAALMNA | |
| SCHEMBL10682462 | 0.85 | MAPT (0.53) | MAPTALDH1A1GAALMNASMN1; SMN2 | |
| SCHEMBL10684372 | 0.85 | MAPT (0.34) | MAPTALDH1A1L3MBTL1GAALMNA | |
| SCHEMBL10676837 | 0.85 | CDC7 (0.42) | MAPTALDH1A1L3MBTL1GAALMNA | |
| SCHEMBL10683120 | 0.85 | PDE3B (0.53) | MAPTALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL10681150 | 0.83 | UCHL1 (0.50) | MAPTALDH1A1L3MBTL1GAALMNA | |
| SCHEMBL10678457 | 0.83 | LMNA (0.40) | MAPTALDH1A1L3MBTL1GAALMNA | |
| SCHEMBL10680367 | 0.83 | GAA (0.43) | MAPTALDH1A1L3MBTL1GAALMNA | |
| SCHEMBL7384614 | 0.80 | PDE3B (0.47) | MAPTALDH1A1L3MBTL1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769380-A | Cardiotonic 5-benzoyl-1,2-dihydro-2-oxo-3-pyridinecarboxylates | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-09-06 | — | — | US | disclosed |