Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10687757 | 0.98 | HDAC1 (0.48) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL10689278 | 0.98 | HDAC1 (0.51) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL10686079 | 0.95 | PSIP1 (0.47) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL10686023 | 0.93 | PSIP1 (0.46) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL10409150 | 0.88 | L3MBTL1 (0.51) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL10409508 | 0.86 | L3MBTL1 (0.50) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL4770148 | 0.84 | GAA (0.47) | L3MBTL1ALDH1A1LMNASMN1; SMN2CYP3A4 | |
| SCHEMBL4766574 | 0.80 | CA1 (0.44) | ALDH1A1PKMSMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL576918 | 0.80 | KEAP1 (0.63) | HDAC1HDAC2HDAC8HDAC3HDAC4 | |
| SCHEMBL4768191 | 0.79 | GAA (0.49) | L3MBTL1ALDH1A1LMNASMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4724235-A | N-(arylthioalkyl)-N'-(aminoalkyl)ureas useful in the treatment of arrhythmia | A. H. ROBINS COMPANY, INCORPORATED (US) | 1988-02-09 | — | — | US | disclosed |
| US-4597902-A | TREATMENT OF CARDIAC ARRHYTHMIAS | A. H. ROBINS COMPANY, INCORPORATED (US) | 1986-07-01 | — | — | US | disclosed |