Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.83 |
| ▸ | AANAT | Q16613 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.66 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | MMP9 | P14780 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29926356 | 0.96 | MTNR1A (0.98) | MTNR1AMEN1KMT2AAANATCYP1A2 | |
| SCHEMBL3806536 | 0.95 | MTNR1A (1.00) | MTNR1AMEN1KMT2AAANATCYP1A2 | |
| SCHEMBL1724741 | 0.95 | MTNR1A (1.00) | MTNR1AMEN1KMT2AAANATCYP1A2 | |
| SCHEMBL1727281 | 0.95 | MTNR1A (1.00) | MTNR1AMEN1KMT2AAANATCYP1A2 | |
| SCHEMBL1726070 | 0.95 | MTNR1A (1.00) | MTNR1AMEN1KMT2AAANATCYP1A2 | |
| SCHEMBL1725354 | 0.95 | MTNR1A (1.00) | MTNR1AMEN1KMT2AAANATCYP1A2 | |
| SCHEMBL1726502 | 0.95 | MTNR1A (1.00) | MTNR1AMEN1KMT2AAANATCYP1A2 | |
| SCHEMBL1066221 | 0.95 | MTNR1A (1.00) | MTNR1AMEN1KMT2AAANATCYP1A2 | |
| SCHEMBL22411433 | 0.95 | MTNR1A (1.00) | MTNR1AMEN1KMT2AAANATCYP1A2 | |
| SCHEMBL1063483 | 0.95 | MTNR1A (1.00) | MTNR1AMEN1KMT2AAANATCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102906159-A | Amine polymers as bile acid sequestrants | RELYPSA INC | 2013-01-30 | — | — | CN | claimed |
| CN-102858817-A | Crosslinked polyvinylamines, polyallylamines and ethyleneimines for use as bile acid sequestrants | RELYPSA INC | 2013-01-02 | — | — | CN | claimed |
| CN-102906159-A | Amine polymers as bile acid sequestrants | RELYPSA INC | 2013-01-30 | — | — | CN | disclosed |
| CN-102858817-A | Crosslinked polyvinylamines, polyallylamines and ethyleneimines for use as bile acid sequestrants | RELYPSA INC | 2013-01-02 | — | — | CN | disclosed |
| US-7872040-B2 | Receptor blocker and vasodilator comprising indole derivative as active ingredient | SOMEI MASANORI | 2011-01-18 | — | — | US | disclosed |
| US-20090005430-A1 | Receptor Blocker and Vasodilator Comprising Indole Derivative as Active Ingredient | NATIONAL UNIVERSITY CORPORATION KANAZAWA UNIVERSITY (JP) | 2009-01-01 | — | — | US | disclosed |
| US-4456607-A | 9-Bromo-hexahydro- and octahydro-indolo[2,3 a]quinolizines and use for increasing blood circulation | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-06-26 | — | — | US | disclosed |
| US-4428877-A | VASODILATORS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1984-01-31 | — | — | US | disclosed |
| US-4315011-A | VASODILATORS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1982-02-09 | — | — | US | disclosed |
| US-4228168-A | ANTI-ANOXIC ACTIVITY | TANABE SEIYAKU CO., LTD. (JP) | 1980-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005430-A1 | Receptor Blocker and Vasodilator Comprising Indole Derivative as Active Ingredient | ADRB2, ADRB1, ADRA2B | MTNR1A 261/4885MEN1 3707/4885KMT2A 1542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.