Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10683094 | 0.81 | ALDH1A1 (0.43) | MAPTALDH1A1TSHRHSD17B10RECQL | |
| SCHEMBL2303054 | 0.79 | LTA4H (0.49) | LTA4HMAPK14METNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL29857909 | 0.78 | LTA4H (0.47) | LTA4HMAPK14METNPC1RAB9A | |
| SCHEMBL7751671 | 0.77 | ALDH1A1 (0.46) | MAPTALDH1A1TSHRHSD17B10RECQL | |
| SCHEMBL2940314 | 0.76 | ALDH1A1 (0.41) | MAPTSMN1; SMN2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL875558 | 0.76 | LTA4H (0.50) | LTA4HMAPK14METNPC1RAB9A | |
| SCHEMBL875218 | 0.72 | NPC1 (0.46) | LTA4HMAPK14METNPC1RAB9A | |
| SCHEMBL67670 | 0.72 | MET (0.49) | LTA4HMAPK14METNPC1RAB9A | |
| SCHEMBL7751907 | 0.70 | ALDH1A1 (0.41) | MAPTHTTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL22234884 | 0.69 | LTA4H (0.54) | LTA4HMAPK14METNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4756739-A | Herbicides | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-12 | — | — | US | disclosed |
| EP-0227047-A2 | Pyridine derivatives and their N-oxides, process for their preparation and their use as intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-01 | — | — | EP | disclosed |