Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10683029 | 0.81 | LTA4H (0.41) | ALDH1A1TSHRHSD17B10RECQLMEN1 | |
| SCHEMBL30827599 | 0.79 | RXRA (0.41) | — | |
| SCHEMBL27252060 | 0.79 | RXRA (0.41) | — | |
| SCHEMBL7751671 | 0.77 | ALDH1A1 (0.46) | ALDH1A1TSHRHSD17B10RECQLMEN1 | |
| SCHEMBL189173 | 0.72 | TRPV4 (0.41) | MAPTKMT2AKDM4E | |
| SCHEMBL7751907 | 0.70 | ALDH1A1 (0.41) | ALDH1A1TSHRHSD17B10RECQLMEN1 | |
| SCHEMBL3073557 | 0.70 | TDP1 (0.51) | ALDH1A1TSHRRECQLMEN1USP2 | |
| SCHEMBL2940314 | 0.69 | ALDH1A1 (0.41) | ALDH1A1TSHRHSD17B10RECQLMEN1 | |
| SCHEMBL1359631 | 0.69 | RECQL (0.33) | ALDH1A1TSHRHSD17B10RECQL | |
| SCHEMBL4432486 | 0.68 | ALDH1A1 (0.54) | ALDH1A1TSHRHSD17B10RECQLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4756739-A | Herbicides | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-07-12 | — | — | US | disclosed |
| EP-0227047-A2 | Pyridine derivatives and their N-oxides, process for their preparation and their use as intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-01 | — | — | EP | disclosed |