Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10685194 | 0.79 | PGR (0.45) | PDE4DPGRALDH1A1MEN1KMT2A | |
| SCHEMBL10688478 | 0.75 | PDE4D (0.49) | PDE4DPGRALDH1A1MEN1KMT2A | |
| SCHEMBL10681618 | 0.70 | KDM4E (0.46) | ALDH1A1MEN1KMT2ATP53HTT | |
| SCHEMBL13032564 | 0.66 | HRH3 (0.56) | ALDH1A1MEN1KMT2ALMNANOS3 | |
| SCHEMBL13948572 | 0.66 | NOS3 (0.37) | PDE4DALDH1A1NOS3NOS1NOS2 | |
| SCHEMBL11570731 | 0.62 | PGR (0.52) | PDE4DPGRALDH1A1MEN1KMT2A | |
| SCHEMBL11571405 | 0.62 | PGR (0.52) | PDE4DPGRMEN1KMT2APDE3B | |
| SCHEMBL23239911 | 0.62 | CYP2A13 (0.54) | ALDH1A1MEN1KMT2ALMNATP53 | |
| SCHEMBL19851997 | 0.61 | DRD2 (0.50) | ALDH1A1MEN1KMT2ASLC6A3 | |
| SCHEMBL8302675 | 0.61 | PGR (0.51) | PDE4DPGRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738961-A | FUNGICIDES | SANKYO COMPANY, LIMITED (JP) | 1988-04-19 | — | — | US | disclosed |
| EP-0072238-B1 | PYRIDAZINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE IN AGRICULTURAL COMPOSITIONS AND THE TREATMENT OF SEED AND PLANTS | SANKYO COMPANY LIMITED (JP) | 1985-11-06 | — | — | EP | disclosed |
| EP-0072238-A1 | Pyridazinone derivatives, their preparation and their use in agricultural compositions and the treatment of seed and plants | SANKYO COMPANY LIMITED (JP) | 1983-02-16 | — | — | EP | disclosed |