Sugi Predict

Sugi Predict / Compounds / SCHEMBL1068504

SCHEMBL1068504

SCHEMBL1068504

CC(C)(C)OC(=O)N1[C@@H](CCO)COC1(C)C

nearest known ligand 0.69

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ SPHK1 Q9NYA1 1/20 0.48
▸ HSD11B2 P80365 1/20 0.38
▸ BRD4 O60885 1/20 0.37
▸ NR1H2 P55055 1/20 0.35
▸ CHRM2 P08172 1/20 0.35
▸ CHRM1 P11229 1/20 0.35
▸ CHRM3 P20309 1/20 0.35
▸ HCRTR2 O43614 1/20 0.34
▸ USP2 O75604 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ DDB1 Q16531 1/20 0.31
▸ CRBN Q96SW2 1/20 0.31
▸ ATM Q13315 2/20 0.31
▸ RECQL P46063 1/20 0.31
▸ CTSK P43235 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15318844 1.00 SPHK1 (0.48) SPHK1HSD11B2BRD4NR1H2CHRM2
SCHEMBL1068506 1.00 SPHK1 (0.48) SPHK1HSD11B2BRD4NR1H2CHRM2
SCHEMBL7305261 0.92 SPHK1 (0.49) SPHK1HSD11B2BRD4NR1H2CHRM2
SCHEMBL6208006 0.92 SPHK1 (0.49) SPHK1HSD11B2BRD4NR1H2CHRM2
SCHEMBL6208002 0.92 SPHK1 (0.49) SPHK1HSD11B2BRD4NR1H2CHRM2
SCHEMBL13040191 0.91 SPHK1 (0.48) SPHK1HSD11B2BRD4NR1H2CHRM2
SCHEMBL8055345 0.91 SPHK1 (0.48) SPHK1HSD11B2BRD4NR1H2CHRM2
SCHEMBL8053046 0.91 SPHK1 (0.48) SPHK1HSD11B2BRD4NR1H2CHRM2
SCHEMBL16053956 0.89 SPHK1 (0.50) SPHK1HSD11B2BRD4NR1H2CHRM2
SCHEMBL31362554 0.89 SPHK1 (0.47) SPHK1HSD11B2BRD4NR1H2CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023092287-A1 HIGH-TRANSPARENCY REACTIVE POLYURETHANE HOT MELT ADHESIVE AND PREPARATION METHOD THEREFOR 广州市白云化工实业有限公司 2023-06-01 — — WO claimed
CN-114045143-A High-transparency reactive polyurethane hot melt adhesive and preparation method thereof 广州市白云化工实业有限公司 2022-02-15 — — CN claimed
US-20260001889-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING SKYHAWK THERAPEUTICS INC (US) 2026-01-01 — — US disclosed
EP-4522622-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING Skyhawk Therapeutics, Inc. (US) 2025-03-19 — — EP disclosed
WO-2024041573-A1 FUSED MULTI-HETEROCYCLIC COMPOUNDS AS KRAS G12D MODULATORS AND USES THEREOF ZAI LAB (SHANGHAI) CO., LTD. (CN) 2024-02-29 — — WO disclosed
CN-114045143-B High-transparency reactive polyurethane hot melt adhesive and preparation method thereof 广州白云科技股份有限公司 2024-02-09 — — CN disclosed
WO-2023220439-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. (US) 2023-11-16 — — WO disclosed
WO-2023220439-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. (US) 2023-11-16 — — WO disclosed
WO-2023092287-A1 HIGH-TRANSPARENCY REACTIVE POLYURETHANE HOT MELT ADHESIVE AND PREPARATION METHOD THEREFOR 广州市白云化工实业有限公司 2023-06-01 — — WO disclosed
CN-114045143-A High-transparency reactive polyurethane hot melt adhesive and preparation method thereof 广州市白云化工实业有限公司 2022-02-15 — — CN disclosed
EP-3134408-B1 FACTOR XIa INHIBITORS MERCK SHARP & DOHME (US) 2020-08-12 — — EP disclosed
US-20090264434-A1 PYRIDAZINONE GLUCOKINASE ACTIVATORS BERTHEL STEVEN JOSEPH 2009-10-22 — — US disclosed
US-20090264434-A1 PYRIDAZINONE GLUCOKINASE ACTIVATORS BERTHEL STEVEN JOSEPH 2009-10-22 — — US disclosed
US-20090264445-A1 PYRROLIDINONE GLUCOKINASE ACTIVATORS BERTHEL STEVEN JOSEPH 2009-10-22 — — US disclosed
US-20090264445-A1 PYRROLIDINONE GLUCOKINASE ACTIVATORS BERTHEL STEVEN JOSEPH 2009-10-22 — — US disclosed
US-20090264445-A1 PYRROLIDINONE GLUCOKINASE ACTIVATORS BERTHEL STEVEN JOSEPH 2009-10-22 — — US disclosed
WO-2009127546-A1 PYRROLIDINONE GLUCOKINASE ACTIVATORS F. HOFFMANN-LA ROCHE AG (CH) 2009-10-22 — — WO disclosed
WO-2009127546-A1 PYRROLIDINONE GLUCOKINASE ACTIVATORS F. HOFFMANN-LA ROCHE AG (CH) 2009-10-22 — — WO disclosed
US-6472533-B1 SUCH AS PHOSPHINE OXAZOLINES; HIGH ENANTIOSELECTIVITY; CATALYSTS FOR SYNTHESIS OF ACTIVE MATERIALS FOR PHARMACEU-TICALS, AGROCHEMICALS, FRAGRANCES AND FOOD ADDITIVES; EFFICIENT THE TEXAS A & M UNIVERSITY SYSTEM 2002-10-29 — — US disclosed
EP-0520336-A2 Aldehyde derivatives and their use as calpain inhibitors FUJIREBIO Inc. (JP) 1992-12-30 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260001889-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING SF3B1, SF3A1, SF3B5 SPHK1 4261/4885HSD11B2 831/4885BRD4 3492/4885
US-20090264445-A1 PYRROLIDINONE GLUCOKINASE ACTIVATORS GCKR, GCK, PDK2 SPHK1 499/4885HSD11B2 1296/4885BRD4 2832/4885
US-20090264434-A1 PYRIDAZINONE GLUCOKINASE ACTIVATORS GCK, GCKR, PDXK SPHK1 756/4885HSD11B2 1460/4885BRD4 2518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.