Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825506 | 0.82 | SLC6A1 (0.47) | KCNH2 | |
| SCHEMBL9692045 | 0.81 | KCNH2 (0.50) | KCNH2 | |
| SCHEMBL9824935 | 0.79 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL9785730 | 0.76 | KCNH2 (0.56) | KCNH2TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL10407771 | 0.74 | KCNH2 (0.53) | KCNH2 | |
| Hydrochloric Acid SCHEMBL10407770 | 0.73 | KCNH2 (0.53) | KCNH2TMEM97SIGMAR1 | |
| Hydrochloric Acid SCHEMBL10408435 | 0.73 | KCNH2 (0.68) | KCNH2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL10407854 | 0.71 | KCNH2 (0.54) | KCNH2TMEM97SIGMAR1 | |
| SCHEMBL9339570 | 0.71 | DRD2 (0.59) | KCNH2 | |
| SCHEMBL10407767 | 0.71 | KCNH2 (0.67) | KCNH2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252005-A1 | Hydrogenated 1-benzooxacycloalkyl-pyridine carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-07 | — | — | EP | claimed |