Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 7/20 | 0.37 |
| ▸ | HTR2A | P28223 | 7/20 | 0.37 |
| ▸ | DRD3 | P35462 | 7/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9692045 | 0.84 | KCNH2 (0.50) | KCNH2DRD2HTR2ADRD3PTGDR2 | |
| SCHEMBL9629777 | 0.84 | MTNR1A (0.42) | DRD2 | |
| Hydrochloric Acid SCHEMBL9630863 | 0.83 | MTNR1A (0.41) | DRD2 | |
| SCHEMBL9825506 | 0.80 | SLC6A1 (0.47) | KCNH2 | |
| SCHEMBL10685083 | 0.79 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL9824689 | 0.78 | MTNR1A (0.46) | DRD2 | |
| SCHEMBL9824929 | 0.78 | KCNH2 (0.49) | KCNH2DRD2HTR2ADRD3 | |
| SCHEMBL9824923 | 0.77 | MALT1 (0.42) | KCNH2DRD2HTR2ADRD3 | |
| Hydrochloric Acid SCHEMBL9824811 | 0.76 | MALT1 (0.41) | KCNH2DRD2HTR2ADRD3 | |
| SCHEMBL9339570 | 0.74 | DRD2 (0.59) | KCNH2DRD2HTR2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252005-B1 | HYDROGENATED 1-BENZOOXACYCLOALKYL-PYRIDINE CARBOXYLIC-ACID COMPOUNDS | CIBA-GEIGY AG (CH) | 1991-07-10 | — | — | EP | claimed |
| EP-0252005-A1 | Hydrogenated 1-benzooxacycloalkyl-pyridine carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-07 | — | — | EP | claimed |
| EP-0252005-B1 | HYDROGENATED 1-BENZOOXACYCLOALKYL-PYRIDINE CARBOXYLIC-ACID COMPOUNDS | CIBA-GEIGY AG (CH) | 1991-07-10 | — | — | EP | disclosed |