Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL394319 | 0.82 | KDM4E (0.47) | ALDH1A1MAPTKDM4EKMT2AL3MBTL1 | |
| SCHEMBL8696589 | 0.81 | CA12 (0.49) | KDM4CALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL4907976 | 0.81 | SMN1; SMN2 (0.50) | ALDH1A1MAPTKDM4EL3MBTL1ALOX15 | |
| Potassium SCHEMBL30402396 | 0.80 | SMN1; SMN2 (0.49) | ALDH1A1MAPTKDM4EL3MBTL1ALOX15 | |
| SCHEMBL2122533 | 0.79 | CHIA (0.43) | MAPTTRPV1PIM1PIM3 | |
| SCHEMBL225760 | 0.77 | ALDH1A1 (0.50) | ALDH1A1TDP1L3MBTL1MLYCDALOX15 | |
| Biphenyl SCHEMBL27395942 | 0.76 | HTR6 (0.48) | ALDH1A1ALOX15CYP3A4PIM1PIM3 | |
| SCHEMBL30331023 | 0.76 | F10 (0.39) | KDM4CALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL8669300 | 0.74 | GPR119 (0.53) | ALDH1A1MAPTMEN1KMT2APTPN11 | |
| SCHEMBL19943248 | 0.73 | MAPT (0.55) | KDM4CALDH1A1MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408745-A1 | PIPERIDINE DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | F. Hoffmann-La Roche AG (CH) | 2012-01-25 | — | — | EP | disclosed |