SCHEMBL11484155

SCHEMBL11484155

COc1ccc(C(=O)c2ccc(N(CCCl)CCCl)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.56
EGFR P00533 4/20 0.54
ERBB2 P04626 4/20 0.54
KMT2A Q03164 2/20 0.51
MEN1 O00255 1/20 0.51
LMNA P02545 1/20 0.51
MAPT P10636 1/20 0.51
MAPK1 P28482 1/20 0.51
RAB9A P51151 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
RXFP1 Q9HBX9 1/20 0.51
ACHE P22303 1/20 0.48
ALDH1A1 P00352 1/20 0.47
GAA P10253 1/20 0.47
TUBB4A P04350 1/20 0.46
TUBB P07437 1/20 0.46
TUBA3C P0DPH7 1/20 0.46
TUBA1B P68363 1/20 0.46
TUBA4A P68366 1/20 0.46
TUBB4B P68371 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL659196 0.87 CA12 (0.46) EGFRERBB2KMT2AMEN1LMNA
SCHEMBL9749949 0.83 MEN1 (0.50) HPGDEGFRERBB2KMT2AMEN1
SCHEMBL11475947 0.82 EGFR (0.60) HPGDEGFRERBB2KMT2AMEN1
SCHEMBL12266656 0.82 EGFR (0.58) HPGDEGFRERBB2KMT2AMEN1
SCHEMBL2496427 0.82 MAPT (0.56) HPGDKMT2AMEN1LMNAMAPT
SCHEMBL11491649 0.80 ALDH1A1 (0.47) HPGDEGFRERBB2KMT2AMEN1
SCHEMBL11483974 0.79 ALDH1A1 (0.64) HPGDEGFRERBB2KMT2AMEN1
SCHEMBL10686398 0.79 EGFR (0.50) EGFRERBB2KMT2AMEN1LMNA
SCHEMBL2170152 0.79 EGFR (0.54) HPGDEGFRERBB2KMT2AMEN1
SCHEMBL19879308 0.78 KMT2A (0.63) HPGDKMT2AMEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4220356-A Recording materials containing chromenoindoles FUJI PHOTO FILM CO., LTD. (JP) 1980-09-02 US disclosed