Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GPR6 | P46095 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 4/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10689343 | 0.77 | SMARCA2 (0.44) | HTTALDH1A1LMNATSHRMEN1 | |
| SCHEMBL18622667 | 0.71 | ALDH1A1 (0.46) | HTTPOLBALDH1A1HPGDTP53 | |
| Bromide SCHEMBL18606181 | 0.70 | ALDH1A1 (0.48) | HTTPOLBALDH1A1HPGDTP53 | |
| SCHEMBL6546292 | 0.66 | NFE2L2 (0.46) | HTTPOLBTP53MEN1KMT2A | |
| SCHEMBL10810584 | 0.64 | CA1 (0.51) | ALDH1A1TP53HSD17B10LMNAMAPT | |
| SCHEMBL16105803 | 0.63 | NPSR1 (0.45) | HTTPOLBTSHRMEN1KMT2A | |
| SCHEMBL10690156 | 0.62 | KCNH2 (0.42) | HTTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8498672 | 0.61 | NPSR1 (0.47) | HTTPOLBALDH1A1TP53MAPT | |
| SCHEMBL4738437 | 0.61 | CES2 (0.60) | HTTPOLBALDH1A1HPGDHSD17B10 | |
| SCHEMBL29726796 | 0.60 | MAPT (0.49) | HTTPOLBALDH1A1TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732989-A | INTERMEDIATES FOR BACTERICIDES | G. D. SEARLE & CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4661602-A | ANTIANAEROBIC AGENTS | G. D. SEARLE & CO. (US) | 1987-04-28 | — | — | US | disclosed |