Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | NCF1 | P14598 | 1/20 | 0.64 |
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | CNR2 | P34972 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.56 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.56 |
| ▸ | NOS1 | P29475 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL578335 | 0.98 | SMN1; SMN2 (0.70) | SMN1; SMN2TDP1NCF1CNR1CNR2 | |
| SCHEMBL17160816 | 0.97 | SMN1; SMN2 (0.68) | SMN1; SMN2TDP1NCF1CNR1CNR2 | |
| SCHEMBL11196105 | 0.86 | NCF1 (0.83) | SMN1; SMN2NCF1HTTKDM4EALDH1A1 | |
| SCHEMBL6818314 | 0.84 | SMN1; SMN2 (0.93) | SMN1; SMN2TDP1HTTKDM4EALDH1A1 | |
| SCHEMBL9025487 | 0.82 | SMN1; SMN2 (0.96) | SMN1; SMN2TDP1HTTKDM4EALDH1A1 | |
| SCHEMBL5256343 | 0.82 | SIGMAR1 (0.58) | SMN1; SMN2TDP1NCF1HTTALDH1A1 | |
| SCHEMBL3641561 | 0.81 | SMN1; SMN2 (1.00) | SMN1; SMN2TDP1HTTKDM4EALDH1A1 | |
| SCHEMBL1651281 | 0.80 | SIGMAR1 (0.67) | SMN1; SMN2TDP1HTTKDM4E | |
| SCHEMBL29197757 | 0.79 | SMN1; SMN2 (0.72) | SMN1; SMN2TDP1HTTKDM4EALDH1A1 | |
| SCHEMBL6813604 | 0.79 | HRH3 (0.69) | SMN1; SMN2HTTKDM4EALDH1A1NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040224364-A1 | Organo-zinc compounds | RIEKE METALS, INC. | 2004-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040224364-A1 | Organo-zinc compounds | ZFX, CXXC5, CXXC4 | SMN1; SMN2 3620/4885TDP1 3516/4885NCF1 195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.