Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 6/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GABRP | O00591 | 4/20 | 0.37 |
| ▸ | GABRD | O14764 | 4/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 4/20 | 0.37 |
| ▸ | GABRE | P78334 | 4/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 4/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 4/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 4/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10679158 | 0.82 | GABRA2 (0.38) | GABRA2GABRB2ALDH1A1GABRPGABRD | |
| SCHEMBL10800326 | 0.78 | GABRA2 (0.35) | GABRA2GABRB2ALDH1A1GABRPGABRD | |
| SCHEMBL16014667 | 0.78 | SMN1; SMN2 (0.41) | ALDH1A1F10HTT | |
| SCHEMBL17359686 | 0.78 | F10 (0.38) | ALDH1A1MAPTF10MEN1KMT2A | |
| SCHEMBL9774785 | 0.76 | ALDH1A1 (0.35) | GABRA2GABRB2ALDH1A1GABRPGABRD | |
| SCHEMBL9774947 | 0.76 | MRGPRX4 (0.37) | GABRA2GABRB2ALDH1A1GABRPGABRD | |
| SCHEMBL9774867 | 0.75 | GABRB3 (0.41) | GABRA2GABRB2ALDH1A1GABRPGABRD | |
| SCHEMBL16022856 | 0.74 | POLB (0.35) | F10 | |
| SCHEMBL17358325 | 0.74 | F10 (0.36) | F10 | |
| SCHEMBL9774928 | 0.74 | GABRA2 (0.38) | GABRA2GABRB2ALDH1A1GABRPGABRD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0259048-A2 | Chemical compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-03-09 | — | — | EP | disclosed |