Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691944 | 0.86 | GUSB (0.38) | TSHRPDE4BPDE4DGUSBALDH1A1 | |
| SCHEMBL10685926 | 0.85 | PDGFRB (0.48) | PDGFRBPDGFRACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10691788 | 0.85 | PDE2A (0.46) | PDGFRBPDGFRACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10689009 | 0.84 | PDE5A (0.39) | PDE4APDE4BPDE4CPDE4DMTNR1A | |
| SCHEMBL10690326 | 0.83 | PDE4A (0.48) | PDGFRBPDGFRACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10692316 | 0.83 | PDGFRB (0.43) | PDGFRBPDGFRACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10611564 | 0.81 | PDGFRB (0.48) | PDGFRBPDGFRACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10690574 | 0.79 | PDE2A (0.51) | CYP3A4CYP2D6CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL10206627 | 0.78 | CYP3A4 (0.46) | PDGFRBPDGFRACYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10685567 | 0.78 | GUSB (0.54) | TSHRGUSBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4722929-A | Novel 2-phenyl-imidazoles and pharmaceutical compositions containing same | DR. KARL THOMAE GMBH (DE) | 1988-02-02 | — | — | US | disclosed |
| EP-0149200-A1 | Novel 2-pnenyl-imidazoles, their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1985-07-24 | — | — | EP | disclosed |