Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | GUSB | P08236 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10685926 | 0.93 | PDGFRB (0.48) | PDGFRBPDGFRAMAPTKDM4ENPSR1 | |
| SCHEMBL10611564 | 0.89 | PDGFRB (0.48) | PDGFRBPDGFRAMAPTKDM4ENPSR1 | |
| SCHEMBL10686647 | 0.88 | PDE2A (0.42) | MAPTKDM4ENPSR1MAPK1GUSB | |
| SCHEMBL10691788 | 0.85 | PDE2A (0.46) | PDGFRBPDGFRAMAPTKDM4ENPSR1 | |
| SCHEMBL10692327 | 0.84 | PDE5A (0.43) | PDGFRBPDGFRAMAPTKDM4EPRMT5 | |
| SCHEMBL10690322 | 0.83 | PDGFRB (0.43) | PDGFRBPDGFRAGUSBMAOBALDH1A1 | |
| SCHEMBL10688930 | 0.82 | MEN1 (0.39) | MAPTKDM4ENPSR1MAPK1GUSB | |
| SCHEMBL10686088 | 0.82 | PDGFRB (0.47) | PDGFRBPDGFRAMAPTKDM4ENPSR1 | |
| SCHEMBL10610920 | 0.81 | GUSB (0.36) | MAPTKDM4ENPSR1GUSBLMNA | |
| SCHEMBL10691944 | 0.79 | GUSB (0.38) | MAPTKDM4ENPSR1MAPK1GUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4722929-A | Novel 2-phenyl-imidazoles and pharmaceutical compositions containing same | DR. KARL THOMAE GMBH (DE) | 1988-02-02 | — | — | US | disclosed |
| EP-0149200-A1 | Novel 2-pnenyl-imidazoles, their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1985-07-24 | — | — | EP | disclosed |