SCHEMBL10690356

SCHEMBL10690356

O=C(c1ccccn1)N(O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.61
CES1 P23141 1/20 0.61
L3MBTL1 Q9Y468 3/20 0.59
LMNA P02545 3/20 0.59
NAPRT Q6XQN6 1/20 0.59
P4HTM Q9NXG6 1/20 0.59
ALDH1A1 P00352 1/20 0.57
KMT2A Q03164 1/20 0.53
GSK3B P49841 1/20 0.52
GAA P10253 1/20 0.49
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
KDM4E B2RXH2 3/20 0.46
MAPT P10636 1/20 0.46
PKM P14618 1/20 0.46
HSD17B10 Q99714 2/20 0.45
TP53 P04637 1/20 0.45
HDAC3 O15379 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC1 Q13547 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11254855 0.83 ALDH1A1 (0.59) CES2CES1L3MBTL1LMNANAPRT
SCHEMBL761925 0.81 ALDH1A1 (0.61) CES2CES1L3MBTL1LMNANAPRT
SCHEMBL18917080 0.81 CES2 (0.59) CES2CES1L3MBTL1LMNANAPRT
SCHEMBL29516254 0.81 ALDH1A1 (0.61) CES2CES1L3MBTL1LMNANAPRT
SCHEMBL4656150 0.81 CES2 (0.59) CES2CES1L3MBTL1LMNANAPRT
SCHEMBL14885759 0.80 LMNA (0.57) CES2CES1L3MBTL1LMNANAPRT
Hydrochloric Acid SCHEMBL16594352 0.79 ALDH1A1 (0.59) CES2CES1L3MBTL1LMNANAPRT
Hydrochloric Acid SCHEMBL31098456 0.79 ALDH1A1 (0.59) CES2CES1L3MBTL1LMNANAPRT
SCHEMBL9130934 0.79 ALDH1A1 (0.53) CES2CES1L3MBTL1LMNANAPRT
SCHEMBL11883872 0.79 CES2 (0.52) CES2CES1L3MBTL1LMNANAPRT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4744819-A 4-oxo pyridinecarboxamide derivatives as plant growth regulators DAICEL CHEMICAL INDUSTRIES LTD. (JP) 1988-05-17 US disclosed