Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11254855 | 0.79 | ALDH1A1 (0.59) | ALDH1A1CES2CES1SMN1; SMN2NPC1 | |
| SCHEMBL10690356 | 0.79 | CES2 (0.61) | ALDH1A1CES2CES1SMN1; SMN2NPC1 | |
| SCHEMBL306106 | 0.79 | ALDH1A1 (0.53) | ALDH1A1CES2CES1SMN1; SMN2NPC1 | |
| SCHEMBL247011 | 0.77 | KDM4E (0.68) | ALDH1A1CES2CES1SMN1; SMN2NPC1 | |
| SCHEMBL30166417 | 0.77 | KDM4E (0.68) | ALDH1A1CES2CES1SMN1; SMN2NPC1 | |
| SCHEMBL29516254 | 0.77 | ALDH1A1 (0.61) | ALDH1A1CES2CES1SMN1; SMN2NPC1 | |
| SCHEMBL29576494 | 0.77 | KDM4E (0.68) | ALDH1A1CES2CES1SMN1; SMN2NPC1 | |
| SCHEMBL761925 | 0.77 | ALDH1A1 (0.61) | ALDH1A1CES2CES1SMN1; SMN2NPC1 | |
| SCHEMBL12985303 | 0.76 | PKM (0.44) | ALDH1A1CES2CES1SMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL31098456 | 0.76 | ALDH1A1 (0.59) | ALDH1A1CES2CES1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5421897-A | Applying liquid composition to surface contaminated with lead, solidifying into matrix which sequesters lead, removing matrix | GRAWE JOHN (US) | 1995-06-06 | — | — | US | disclosed |