Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11062345 | 0.86 | ATM (0.47) | ALDH1A1L3MBTL1MAPTGAANPSR1 | |
| SCHEMBL11073531 | 0.85 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1MAPTGAANPSR1 | |
| SCHEMBL11071747 | 0.85 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1MAPTGAANPSR1 | |
| SCHEMBL11065598 | 0.80 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1MAPTGAANPSR1 | |
| SCHEMBL10689226 | 0.79 | KDM4E (0.41) | ALDH1A1L3MBTL1MAPTGAANPSR1 | |
| SCHEMBL11066781 | 0.78 | GHSR (0.39) | ALDH1A1L3MBTL1MAPTGAANPSR1 | |
| SCHEMBL11073178 | 0.76 | CA2 (0.43) | ALDH1A1L3MBTL1MAPTGAANPSR1 | |
| SCHEMBL11065463 | 0.74 | ATM (0.48) | ALDH1A1L3MBTL1MAPTGAAHTT | |
| SCHEMBL10692313 | 0.73 | MAOB (0.38) | ALDH1A1L3MBTL1MAPTGAAMAPK1 | |
| SCHEMBL27884544 | 0.72 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1MAPTGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732991-A | Substituted phthalides | HILTON DAVIS CHEMICAL CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4595768-A | 3-(substituted phenyl)phthalides | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-06-17 | — | — | US | disclosed |