Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.63 |
| ▸ | ACE | P12821 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | ECE1 | P42892 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | LAP3 | P28838 | 3/20 | 0.49 |
| ▸ | ANPEP | P15144 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368279 | 0.84 | ACE (0.65) | MMEACEECE1 | |
| SCHEMBL7372720 | 0.83 | ACE (0.63) | MMEACEECE1 | |
| SCHEMBL10447979 | 0.83 | MME (0.81) | MMEACEALDH1A1ECE1HPGD | |
| SCHEMBL10694679 | 0.83 | CYP1A2 (0.61) | MMEALDH1A1ECE1HPGDMAPK1 | |
| SCHEMBL2224984 | 0.79 | LAP3 (0.58) | LAP3ANPEP | |
| SCHEMBL7103054 | 0.79 | MME (0.74) | MMEACEALDH1A1ECE1HPGD | |
| SCHEMBL825762 | 0.79 | MME (0.74) | MMEACEALDH1A1ECE1HPGD | |
| SCHEMBL11805463 | 0.78 | ACE (0.69) | MMEACEALDH1A1ECE1HPGD | |
| SCHEMBL8432471 | 0.78 | MME (0.79) | MMEACEALDH1A1ECE1HPGD | |
| SCHEMBL7372721 | 0.78 | ACE (0.50) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738803-A | ENZYME INHIBITORS | ROQUES BERNARD (FR) | 1988-04-19 | — | — | US | disclosed |
| US-4618708-A | ENKEPHALINASE INHIBITOR, ANALGESICS, ANTIDEPRESSANT, ANTIDIARRHEA, OR HYPOTENSIVE AGENT | ROQUES BERNARD (FR) | 1986-10-21 | — | — | US | disclosed |