Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10686865 | 0.83 | NR1H4 (0.44) | GAATSHRKMT2AATMKDM4E | |
| Benzene SCHEMBL10690567 | 0.82 | KMT2A (0.46) | GAASMN1; SMN2TSHRKMT2ACYP2D6 | |
| SCHEMBL9789350 | 0.80 | HTT (0.53) | GAASMN1; SMN2ALDH1A1ATMKDM4E | |
| SCHEMBL11851628 | 0.80 | GAA (0.49) | GAASMN1; SMN2TSHRALDH1A1CYP2D6 | |
| SCHEMBL9074960 | 0.77 | TSHR (0.47) | GAASMN1; SMN2TSHRALDH1A1KMT2A | |
| SCHEMBL30009742 | 0.77 | HIF1A (0.51) | GAAALDH1A1KMT2AMEN1 | |
| SCHEMBL9074962 | 0.76 | CA12 (0.58) | GAASMN1; SMN2TSHRKMT2ACYP2D6 | |
| SCHEMBL9124654 | 0.75 | GAA (0.44) | GAASMN1; SMN2TSHRALDH1A1KMT2A | |
| SCHEMBL3834699 | 0.75 | ALDH1A1 (0.57) | GAATSHRALDH1A1CYP2D6GLA | |
| SCHEMBL9124659 | 0.75 | GAA (0.44) | GAASMN1; SMN2TSHRALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251079-B1 | 3-SUBSTITUTED 1-(2-HALOGENOALKOXY-BENZENSULFONYL)-3-HETEROARYLUREA | BAYER AG (DE) | 1993-05-19 | — | — | EP | claimed |
| EP-0251079-B1 | 3-SUBSTITUTED 1-(2-HALOGENOALKOXY-BENZENSULFONYL)-3-HETEROARYLUREA | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |