Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 4/20 | 0.47 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9852795 | 0.89 | ALPL (0.45) | ALPLSLC40A1MRGPRX1PTGER4SLC22A12 | |
| SCHEMBL30549039 | 0.80 | ALPL (0.47) | ALPLSLC40A1MRGPRX1PTGER4SLC22A12 | |
| SCHEMBL10686865 | 0.78 | NR1H4 (0.44) | ALPLSLC40A1MRGPRX1PTGER4SLC22A12 | |
| SCHEMBL25248899 | 0.77 | ALPL (0.49) | ALPLSLC40A1MRGPRX1PTGER4SLC22A12 | |
| Benzene SCHEMBL10690567 | 0.77 | KMT2A (0.46) | ALPLSLC40A1MRGPRX1PTGER4SLC22A12 | |
| SCHEMBL9618654 | 0.73 | FBP1 (0.48) | ALPLSLC40A1MRGPRX1PTGER4SLC22A12 | |
| SCHEMBL7227358 | 0.73 | ALPL (0.44) | ALPLSLC40A1MRGPRX1PTGER4SLC22A12 | |
| SCHEMBL7227108 | 0.71 | FBP1 (0.49) | ALPLSLC40A1MRGPRX1PTGER4SLC22A12 | |
| SCHEMBL10695861 | 0.70 | ALDH1A1 (0.48) | ALPLSLC40A1SLC22A12IDH1 | |
| SCHEMBL8229520 | 0.70 | ALPL (0.52) | ALPLSLC40A1MRGPRX1SLC22A12BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0444286-A1 | Sulphonylated pyrimidine carboxylic acid amides | BAYER AG (DE) | 1991-09-04 | — | — | EP | disclosed |