Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464358 | 0.78 | ALDH1A1 (0.57) | KMT2AMEN1ALDH1A1LMNATSHR | |
| SCHEMBL28267062 | 0.76 | CYP11B1 (0.47) | KMT2AMEN1MAPK1ALDH1A1LMNA | |
| SCHEMBL8654494 | 0.76 | KMT2A (0.45) | KMT2AMEN1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL10690629 | 0.76 | TBXAS1 (0.55) | KMT2AMAPK1ALDH1A1ALOX15TBXAS1 | |
| SCHEMBL27713433 | 0.74 | KMT2A (0.49) | KMT2AMEN1MAPK1ALDH1A1LMNA | |
| SCHEMBL9897914 | 0.74 | ALDH1A1 (0.47) | KMT2AMAPK1ALDH1A1ALOX15TSHR | |
| SCHEMBL7619544 | 0.73 | KMT2A (0.43) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28469789 | 0.73 | CYP11B1 (0.49) | KMT2AMEN1MAPK1ALDH1A1LMNA | |
| SCHEMBL6411427 | 0.72 | KMT2A (0.42) | KMT2AMEN1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8746193 | 0.70 | GAA (0.48) | KMT2AMEN1ALDH1A1HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732989-A | INTERMEDIATES FOR BACTERICIDES | G. D. SEARLE & CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4661602-A | ANTIANAEROBIC AGENTS | G. D. SEARLE & CO. (US) | 1987-04-28 | — | — | US | disclosed |