Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 6/20 | 0.55 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | QPCT | Q16769 | 1/20 | 0.50 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.50 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.50 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690615 | 0.76 | KMT2A (0.51) | TBXAS1KMT2APOLBCYP11B1CYP11B2 | |
| SCHEMBL14027194 | 0.75 | TBXAS1 (0.62) | TBXAS1LTA4HKMT2ACYP19A1CYP1A2 | |
| SCHEMBL9309031 | 0.75 | KMT2A (0.61) | KMT2AALDH1A1 | |
| SCHEMBL27538763 | 0.72 | EGLN3 (0.49) | TBXAS1KMT2AALDH1A1MAPK1 | |
| SCHEMBL9897914 | 0.72 | ALDH1A1 (0.47) | TBXAS1KMT2APOLBALDH1A1ALOX15 | |
| Phenylmethanesulfonic Acid SCHEMBL27713435 | 0.72 | ALDH1A1 (0.51) | TBXAS1CYP19A1CYP1A2POLBCYP3A4 | |
| SCHEMBL409741 | 0.72 | HMOX1 (0.72) | TBXAS1LTA4HKMT2ACYP19A1CYP1A2 | |
| SCHEMBL28762574 | 0.71 | TBXAS1 (0.57) | TBXAS1LTA4HKMT2ACYP19A1CYP1A2 | |
| SCHEMBL7619550 | 0.71 | KMT2A (0.57) | KMT2AALDH1A1 | |
| SCHEMBL29043751 | 0.71 | HMOX1 (0.59) | TBXAS1LTA4HKMT2ACYP19A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732989-A | INTERMEDIATES FOR BACTERICIDES | G. D. SEARLE & CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4661602-A | ANTIANAEROBIC AGENTS | G. D. SEARLE & CO. (US) | 1987-04-28 | — | — | US | disclosed |