Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.55 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.55 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.55 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9393592 | 0.89 | MAPT (0.56) | ALDH1A1MAPTTSHRMAPK1CA12 | |
| SCHEMBL10693790 | 0.88 | KMT2A (0.60) | KMT2AMEN1ALDH1A1TSHRMAPK1 | |
| SCHEMBL8107748 | 0.88 | HTT (0.57) | KMT2AMEN1ALDH1A1ADRB2PLAAT3 | |
| SCHEMBL10693452 | 0.85 | SMN1; SMN2 (0.57) | KMT2AMEN1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL742343 | 0.84 | KMT2A (0.71) | KMT2AMEN1ALDH1A1ADRB2PLAAT3 | |
| SCHEMBL10692448 | 0.84 | POLB (0.59) | KMT2AALDH1A1TSHRHPGDSMN1; SMN2 | |
| SCHEMBL8098635 | 0.83 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1ADRB2PLAAT3 | |
| SCHEMBL6094268 | 0.83 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1ADRB2PLAAT3 | |
| SCHEMBL8428854 | 0.82 | ALDH1A1 (0.61) | KMT2AMEN1ALDH1A1ADRB2PLAAT3 | |
| SCHEMBL11509318 | 0.82 | ALDH1A1 (0.61) | KMT2AMEN1ALDH1A1ADRB2PLAAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | claimed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | claimed |
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| US-4518789-A | Phenyl alpha-acyloxyacetamide derivatives and their therapeutic use | YU RUEY J | 1985-05-21 | — | — | US | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |