Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CTSD | P07339 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690654 | 0.88 | KMT2A (0.59) | KMT2AMEN1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL10693524 | 0.84 | KMT2A (0.70) | KMT2AALDH1A1PKMTSHRRAB9A | |
| SCHEMBL4158526 | 0.83 | PKM (0.62) | KMT2AMEN1ALDH1A1PKMTSHR | |
| SCHEMBL4158522 | 0.83 | PKM (0.62) | KMT2AMEN1ALDH1A1PKMTSHR | |
| SCHEMBL4162007 | 0.83 | PKM (0.62) | KMT2AMEN1ALDH1A1PKMTSHR | |
| SCHEMBL6093048 | 0.83 | ERCC1 (0.66) | KMT2AMEN1ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL10692649 | 0.81 | PKM (0.76) | KMT2AMEN1ALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL9502645 | 0.80 | PKM (0.59) | KMT2AMEN1ALDH1A1PKMTSHR | |
| SCHEMBL10689090 | 0.80 | ALDH1A1 (0.69) | KMT2AMEN1ALDH1A1PKMTSHR | |
| SCHEMBL9393592 | 0.77 | MAPT (0.56) | ALDH1A1SMN1; SMN2POLBTSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0098743-B1 | PHENYL ALPHA-ACYLOXYACETAMIDE DERIVATES AND THEIR THERAPEUTIC USE | Yu, Ruey J., Dr. (US) | 1988-09-28 | — | — | EP | disclosed |
| EP-0098743-A1 | Phenyl alpha-acyloxyacetamide derivates and their therapeutic use | Yu, Ruey J., Dr. (US) | 1984-01-18 | — | — | EP | disclosed |