Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.64 |
| ▸ | RXRA | P19793 | 1/20 | 0.60 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.59 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.59 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | PTPRC | P08575 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | PPARD | Q03181 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2087592 | 0.88 | MAOB (0.68) | L3MBTL1POLBSMN1; SMN2PTPRCPTPN1 | |
| SCHEMBL694844 | 0.88 | PKM (0.59) | L3MBTL1NR4A2RXRANR4A1NR4A3 | |
| SCHEMBL30765113 | 0.87 | PARP10 (0.65) | L3MBTL1ALDH1A1GAAPARP14PARP10 | |
| SCHEMBL695301 | 0.86 | L3MBTL1 (0.54) | L3MBTL1NR4A2RXRANR4A1NR4A3 | |
| SCHEMBL1007847 | 0.85 | L3MBTL1 (0.65) | L3MBTL1NR4A2ALKBH1NPC1RAB9A | |
| SCHEMBL6963910 | 0.85 | L3MBTL1 (0.81) | L3MBTL1NR4A2NR4A1NR4A3ALKBH1 | |
| SCHEMBL8890296 | 0.84 | ALDH1A1 (0.61) | L3MBTL1RXRANPC1POLBRAB9A | |
| SCHEMBL6857126 | 0.84 | NR4A2 (0.77) | L3MBTL1NR4A2RXRANR4A1NR4A3 | |
| SCHEMBL4779293 | 0.84 | ABCB1 (0.62) | L3MBTL1ALKBH1MEN1KMT2AALDH1A1 | |
| SCHEMBL11605162 | 0.83 | MEN1 (0.58) | L3MBTL1SMN1; SMN2PTPRCPTPN1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4098816-A | HYPOGLYCEMIC AGENTS AND ANTILIPEMIC AGENTS | BEECHAM GROUP LIMITED (GB) | 1978-07-04 | — | — | US | claimed |
| US-4722929-A | Novel 2-phenyl-imidazoles and pharmaceutical compositions containing same | DR. KARL THOMAE GMBH (DE) | 1988-02-02 | — | — | US | disclosed |
| US-4098816-A | HYPOGLYCEMIC AGENTS AND ANTILIPEMIC AGENTS | BEECHAM GROUP LIMITED (GB) | 1978-07-04 | — | — | US | disclosed |