Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | TTR | P02766 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8891792 | 0.89 | TSHR (0.63) | ALDH1A1GAAMEN1KMT2ACYP1A2 | |
| SCHEMBL8888574 | 0.89 | ALDH1A1 (0.59) | ALDH1A1GAAMEN1KMT2ACYP1A2 | |
| SCHEMBL10690676 | 0.84 | L3MBTL1 (0.65) | ALDH1A1GAAMEN1KMT2APOLB | |
| SCHEMBL12354253 | 0.83 | TSHR (0.70) | ALDH1A1GAAMEN1KMT2ACYP1A2 | |
| SCHEMBL8890162 | 0.82 | KMT2A (0.53) | ALDH1A1GAATTRMEN1KMT2A | |
| SCHEMBL4449146 | 0.81 | NR4A2 (0.56) | GAAMEN1KMT2APOLBRAB9A | |
| SCHEMBL31482052 | 0.81 | MEN1 (0.55) | ALDH1A1GAAMEN1KMT2ATSHR | |
| SCHEMBL8892297 | 0.81 | RXRA (0.54) | TTRMEN1KMT2AL3MBTL1RAB9A | |
| SCHEMBL9363785 | 0.80 | ALDH1A1 (0.56) | ALDH1A1GAAMEN1KMT2ACYP1A2 | |
| SCHEMBL7368821 | 0.79 | CA12 (0.67) | ALDH1A1TTRMEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997003967-A1 | SUBSTITUTED AROMATIC COMPOUNDS AND THEIR PHARMACEUTICAL USE | RHONE-POULENC RORER LIMITED (GB) | 1997-02-06 | — | — | WO | disclosed |