Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10685590 | 0.99 | APEX1 (0.41) | APEX1ALDH1A1HSD17B10SMN1; SMN2POLB | |
| Tiprotimod SCHEMBL1684013 | 0.95 | APEX1 (0.44) | APEX1ALDH1A1HSD17B10SMN1; SMN2POLB | |
| SCHEMBL10694025 | 0.91 | APEX1 (0.53) | APEX1ALDH1A1HSD17B10SMN1; SMN2POLB | |
| SCHEMBL10690648 | 0.85 | TSHR (0.41) | APEX1ALDH1A1HSD17B10SMN1; SMN2POLB | |
| SCHEMBL10688579 | 0.85 | LDHA (0.40) | APEX1ALDH1A1HSD17B10SMN1; SMN2POLB | |
| SCHEMBL9749776 | 0.84 | APEX1 (0.44) | APEX1ALDH1A1HSD17B10SMN1; SMN2POLB | |
| SCHEMBL10685537 | 0.83 | TSHR (0.39) | APEX1ALDH1A1HSD17B10SMN1; SMN2POLB | |
| Tiprotimod SCHEMBL9509661 | 0.83 | SMN1; SMN2 (0.35) | APEX1ALDH1A1HSD17B10SMN1; SMN2POLB | |
| SCHEMBL10691191 | 0.81 | ALDH1A1 (0.40) | ALDH1A1HSD17B10SMN1; SMN2POLBGAA | |
| SCHEMBL9749252 | 0.81 | GAA (0.51) | ALDH1A1HSD17B10POLBHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| EP-0194572-A1 | Heterocyclic sulfides, process for their preparation and Medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-17 | — | — | EP | disclosed |