Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 4/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 4/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.38 |
| ▸ | PRNP | P04156 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tiprotimod SCHEMBL1684013 | 0.92 | APEX1 (0.44) | APEX1ALDH1A1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL10690778 | 0.91 | APEX1 (0.42) | APEX1ALDH1A1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL10685590 | 0.90 | APEX1 (0.41) | APEX1ALDH1A1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL10688579 | 0.88 | LDHA (0.40) | APEX1ALDH1A1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL7818029 | 0.86 | APEX1 (0.37) | APEX1ALDH1A1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL9749252 | 0.84 | GAA (0.51) | ALDH1A1HSD17B10TSHRHPGDPOLB | |
| SCHEMBL10691191 | 0.84 | ALDH1A1 (0.40) | ALDH1A1HSD17B10SMN1; SMN2POLBGAA | |
| SCHEMBL13766692 | 0.84 | ALDH1A1 (0.36) | APEX1ALDH1A1HSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL11120071 | 0.83 | GAA (0.36) | APEX1ALDH1A1HSD17B10HPGDPOLB | |
| SCHEMBL10690648 | 0.82 | TSHR (0.41) | APEX1ALDH1A1HSD17B10TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |