Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10685537 | 0.91 | TSHR (0.39) | TSHRMAPTALDH1A1RAB9AHTT | |
| Tiprotimod SCHEMBL1684013 | 0.89 | APEX1 (0.44) | TSHRMAPTALDH1A1RAB9AHTT | |
| SCHEMBL10690778 | 0.85 | APEX1 (0.42) | TSHRMAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10685590 | 0.84 | APEX1 (0.41) | TSHRALDH1A1LMNASMN1; SMN2POLB | |
| SCHEMBL13471446 | 0.82 | MAPT (0.42) | TSHRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10694025 | 0.82 | APEX1 (0.53) | TSHRALDH1A1HTTSMN1; SMN2L3MBTL1 | |
| Tiprotimod SCHEMBL9509661 | 0.80 | SMN1; SMN2 (0.35) | TSHRMAPTALDH1A1RAB9AHTT | |
| SCHEMBL10688579 | 0.79 | LDHA (0.40) | TSHRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL13766692 | 0.79 | ALDH1A1 (0.36) | TSHRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10691175 | 0.79 | TSHR (0.41) | TSHRMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |