Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.44 |
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 3/20 | 0.37 |
| ▸ | HTR1B | P28222 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | HTR1F | P30939 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | HTR1E | P28566 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800355 | 0.81 | HTR6 (0.55) | HTR6HTR1AHTR2AHTR2BHTR1D | |
| Hydrochloric Acid SCHEMBL9800379 | 0.80 | HTR6 (0.54) | HTR6HTR1AHTR2AHTR2BHTR1D | |
| Hydrochloric Acid SCHEMBL9800411 | 0.79 | HTR6 (0.53) | HTR6HTR1AHTR2AHTR2BHTR1D | |
| SCHEMBL10691162 | 0.79 | HTR6 (0.57) | HTR6HTR2A | |
| SCHEMBL10695378 | 0.78 | HTR6 (0.58) | HTR6HTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL9800371 | 0.78 | HTR6 (0.44) | HTR6HTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL10690634 | 0.77 | HTR6 (0.59) | HTR6HTR7 | |
| SCHEMBL10494786 | 0.76 | OPRM1 (0.39) | HTR6HTR2AHTR1D | |
| SCHEMBL10687919 | 0.75 | HTR6 (0.63) | HTR6HTR1AHTR1DHTR1BDRD2 | |
| SCHEMBL10691119 | 0.75 | HTR6 (0.53) | HTR6HTR1AHTR2AHTR2BHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4785016-A | VASOCONSTRICTION, MIGRAINES ALKANEAMINO, ALKANE SULFONAMIDE INDOLES | GLAXO GROUP LIMITED (GB) | 1988-11-15 | — | — | US | disclosed |