Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9800371 | 0.89 | HTR6 (0.44) | HTR6HDAC1HDAC10HDAC8HDAC6 | |
| SCHEMBL10687919 | 0.86 | HTR6 (0.63) | HTR6 | |
| SCHEMBL9800355 | 0.86 | HTR6 (0.55) | HTR6HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL9800379 | 0.85 | HTR6 (0.54) | HTR6HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL9800411 | 0.84 | HTR6 (0.53) | HTR6HTR2AHTR2C | |
| SCHEMBL10695378 | 0.83 | HTR6 (0.58) | HTR6 | |
| SCHEMBL10690634 | 0.81 | HTR6 (0.59) | HTR6 | |
| SCHEMBL9687324 | 0.81 | HTR1A (0.57) | HTR6HTR2AHTR2CHDAC1HDAC10 | |
| Hydrochloric Acid SCHEMBL9687692 | 0.80 | HTR1A (0.56) | HTR6HTR2AHTR2CHDAC1HDAC10 | |
| SCHEMBL10690810 | 0.79 | HTR6 (0.44) | HTR6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4785016-A | VASOCONSTRICTION, MIGRAINES ALKANEAMINO, ALKANE SULFONAMIDE INDOLES | GLAXO GROUP LIMITED (GB) | 1988-11-15 | — | — | US | disclosed |