Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | SCD | O00767 | 7/20 | 0.38 |
| ▸ | CBFB | Q13951 | 1/20 | 0.37 |
| ▸ | FADS1 | O60427 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694761 | 0.90 | KDR (0.38) | NPBWR1SCDCBFBFADS1PDGFRB | |
| SCHEMBL9252121 | 0.79 | DAO (0.50) | PDGFRBFGFR1KDR | |
| SCHEMBL7502200 | 0.79 | KDR (0.40) | PDGFRBFGFR1KDR | |
| SCHEMBL10686471 | 0.79 | KDR (0.37) | PDGFRBFGFR1KDR | |
| SCHEMBL7499608 | 0.77 | KDR (0.60) | PDGFRBFGFR1KDR | |
| Water SCHEMBL10691885 | 0.76 | KDM4E (0.42) | PDGFRBFGFR1KDR | |
| SCHEMBL10691865 | 0.73 | GRIN2D (0.46) | — | |
| SCHEMBL7506795 | 0.72 | ALDH1A1 (0.51) | PDGFRBKDR | |
| SCHEMBL10691644 | 0.71 | DAO (0.50) | PDGFRBFGFR1KDR | |
| SCHEMBL7503986 | 0.71 | IDH1 (0.43) | PDGFRBFGFR1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4735948-A | (1H-tetrazol-5-yl)-2(1H)-quinolinones and-naphthyridones and antiallergic use thereof | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-04-05 | — | — | US | disclosed |
| EP-0120483-B1 | (1H-TETRAZOL-5-YL)-2(1H)-QUINOLINONES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-04-01 | — | — | EP | disclosed |