Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SGMS2 | Q8NHU3 | 8/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9330242 | 0.77 | KDM4C (0.32) | KDM4C | |
| SCHEMBL8601015 | 0.76 | MEN1 (0.44) | ALDH1A1MEN1KMT2ASGMS2CCR5 | |
| SCHEMBL10691066 | 0.74 | DHFR (0.39) | ALDH1A1MEN1KMT2ASGMS2CCR5 | |
| SCHEMBL6200378 | 0.74 | GAA (0.42) | ALDH1A1MEN1KMT2ASGMS2LMNA | |
| SCHEMBL7108953 | 0.73 | POLB (0.34) | MEN1KMT2ACCR5SLC6A3HPGD | |
| SCHEMBL772662 | 0.72 | KDM4C (0.47) | ALDH1A1MEN1KMT2ASGMS2CCR5 | |
| SCHEMBL9332566 | 0.72 | HTR1A (0.31) | HTR1AL3MBTL1 | |
| SCHEMBL8350940 | 0.72 | MEN1 (0.50) | ALDH1A1MEN1KMT2ASGMS2CCR5 | |
| SCHEMBL8601204 | 0.72 | CCR5 (0.45) | ALDH1A1MEN1KMT2ASGMS2CCR5 | |
| SCHEMBL27252708 | 0.70 | MAPT (0.44) | ALDH1A1MEN1KMT2ASGMS2CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4761420-A | CARDIOVASCULAR DISORDERS | LABORATOIRES SYNTEX S.A. (FR) | 1988-08-02 | — | — | US | disclosed |