Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601015 | 0.84 | MEN1 (0.44) | DHFRKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL27252708 | 0.81 | MAPT (0.44) | DHFRKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL8601204 | 0.80 | CCR5 (0.45) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL10745934 | 0.80 | PTPN1 (0.44) | DHFRPTPN1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7241509 | 0.78 | KMT2A (0.45) | PTPN1KMT2AALDH1A1TDP1HTR1A | |
| SCHEMBL10691070 | 0.74 | ALDH1A1 (0.37) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL8601010 | 0.74 | LMNA (0.46) | DHFRKMT2AMEN1MAPTL3MBTL1 | |
| SCHEMBL772662 | 0.73 | KDM4C (0.47) | KMT2AMEN1ALDH1A1MAPTMAPK1 | |
| SCHEMBL27252707 | 0.73 | DHFR (0.54) | DHFRMAOAMAOB | |
| SCHEMBL10691077 | 0.73 | HTR1A (0.41) | DHFRKMT2AMEN1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4761420-A | CARDIOVASCULAR DISORDERS | LABORATOIRES SYNTEX S.A. (FR) | 1988-08-02 | — | — | US | disclosed |
| EP-0249245-A2 | Antihypertensive dihydropyridine derivatives | LABORATOIRES SYNTEX S.A. (FR) | 1987-12-16 | — | — | EP | disclosed |