Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692036 | 0.82 | MKNK1 (0.40) | — | |
| SCHEMBL10550925 | 0.69 | ALDH1A1 (0.46) | CYP11B2 | |
| SCHEMBL11622951 | 0.67 | ALDH1A1 (0.41) | CYP3A4GAACYP2C9CYP2C19 | |
| SCHEMBL10548057 | 0.66 | CYP11B2 (0.64) | CYP11B2 | |
| SCHEMBL10737848 | 0.63 | MAPT (0.45) | GAACYP2C9CYP2C19 | |
| SCHEMBL9203937 | 0.57 | ACHE (0.34) | — | |
| SCHEMBL11073696 | 0.55 | PDE3B (0.50) | CYP11B2 | |
| SCHEMBL2616405 | 0.54 | ALDH1A1 (0.55) | CYP11B2GAACYP2C9CYP2C19 | |
| SCHEMBL8245080 | 0.54 | CYP11B1 (0.56) | CYP11B2GAACYP2C9 | |
| SCHEMBL5100976 | 0.54 | CYP11B1 (0.53) | CYP11B2GAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255704-A2 | Pyridazinone derivatives, process for their preparation and their use as medicines | Roche Diagnostics GmbH (DE) | 1988-02-10 | — | — | EP | disclosed |