SCHEMBL587388

SCHEMBL587388

O=S(=O)(c1ccccc1CCCl)c1ccccc1CCCl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.41
MMP2 P08253 7/20 0.39
MMP12 P39900 7/20 0.39
MMP13 P45452 7/20 0.39
MMP14 P50281 7/20 0.39
MMP9 P14780 6/20 0.39
MMP8 P22894 6/20 0.39
MMP16 P51512 6/20 0.39
MMP1 P03956 5/20 0.39
MMP3 P08254 5/20 0.39
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP2D6 P10635 1/20 0.35
HSD11B1 P28845 1/20 0.35
CTSB P07858 1/20 0.34
LOXL2 Q9Y4K0 2/20 0.34
PTGES2 Q9H7Z7 1/20 0.34
PTGDR2 Q9Y5Y4 2/20 0.33
PLCG1 P19174 1/20 0.33
NOX4 Q9NPH5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10682236 0.88 GAA (0.39) GAAMMP2MMP12MMP13MMP14
SCHEMBL11254980 0.85 ALDH1A1 (0.38) GAAMMP2MMP12MMP13MMP14
SCHEMBL3066940 0.83 MYC (0.42) GAAMMP2MMP12MMP13MMP14
SCHEMBL10691220 0.83 CA2 (0.47) PTGES2
SCHEMBL7623115 0.83 MEN1 (0.42) MEN1KMT2ACYP2D6HSD11B1CTSB
SCHEMBL3535459 0.82 GAA (0.44) GAAMMP2MMP12MMP13MMP14
SCHEMBL6680949 0.78 TAAR1 (0.50) GAAMEN1KMT2ALOXL2
SCHEMBL5146232 0.78 MMP2 (0.42) GAAMMP2MMP12MMP13MMP14
SCHEMBL11889488 0.78 CTSB (0.42) GAAMMP2MMP12MMP13MMP14
SCHEMBL10690933 0.76 GABRA1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118763273-A Sulfonyl deep eutectic polymer electrolyte and preparation and application thereof 青岛赛锂达储能产业技术研究院有限公司 2024-10-11 CN claimed
CN-105175397-A Synthesis method of eletriptan hydrobromate SHANGHAI MODERN HASEN SHANGQIU PHARMACEUTICAL CO LTD 2015-12-23 CN claimed
CN-104531397-A Cleaning solution for sheet glass substrate thinning pre-cleaning, and application thereof HUIJING DISPLAY TECHNOLOGY SUZHOU CO LTD 2015-04-22 CN claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
CN-118763273-A Sulfonyl deep eutectic polymer electrolyte and preparation and application thereof 青岛赛锂达储能产业技术研究院有限公司 2024-10-11 CN disclosed
US-9494862-B2 Resist underlayer film forming composition containing silicon having sulfone structure and amine structure NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-11-15 US disclosed
CN-105175397-A Synthesis method of eletriptan hydrobromate SHANGHAI MODERN HASEN SHANGQIU PHARMACEUTICAL CO LTD 2015-12-23 CN disclosed
CN-105175397-A Synthesis method of eletriptan hydrobromate SHANGHAI MODERN HASEN SHANGQIU PHARMACEUTICAL CO LTD 2015-12-23 CN disclosed
US-20150159045-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION CONTAINING SILICON HAVING SULFONE STRUCTURE AND AMINE STRUCTURE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-06-11 US disclosed
US-4895840-A ANTIARRHYTHMIA AGENTS A. H. ROBINS COMPANY, INCORPORATED (US) 1990-01-23 US disclosed
EP-0295010-A1 Derivatives of alkylaminoalkyl ureas and cyanoguanidines A.H. ROBINS COMPANY, INCORPORATED (US) 1988-12-14 EP disclosed
US-4724235-A N-(arylthioalkyl)-N'-(aminoalkyl)ureas useful in the treatment of arrhythmia A. H. ROBINS COMPANY, INCORPORATED (US) 1988-02-09 US disclosed
US-4597902-A TREATMENT OF CARDIAC ARRHYTHMIAS A. H. ROBINS COMPANY, INCORPORATED (US) 1986-07-01 US disclosed
EP-0066415-B1 N-(ARYLTHIOALKYL)-N'-(AMINOALKYL)UREAS A.H. ROBINS COMPANY, INCORPORATED (US) 1985-10-02 EP disclosed
EP-0066415-A2 N-(arylthioalkyl)-N'-(aminoalkyl)ureas A.H. ROBINS COMPANY, INCORPORATED (US) 1982-12-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150159045-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION CONTAINING SILICON HAVING SULFONE STRUCTURE AND AMINE STRUCTURE SETDB1, SMC1A, KDM1A GAA 1100/4885MMP2 3073/4885MMP12 2753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.