Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL900706 | 0.77 | DRD1 (0.38) | ALOX15GFERADAM17DRD1ALDH1A1 | |
| SCHEMBL900696 | 0.77 | DRD1 (0.38) | ALOX15GFERADAM17DRD1ALDH1A1 | |
| SCHEMBL1067603 | 0.76 | DRD1 (0.41) | ALOX15GFERADAM17DRD1ALDH1A1 | |
| SCHEMBL900115 | 0.76 | DRD1 (0.37) | ALOX15GFERADAM17DRD1ALDH1A1 | |
| SCHEMBL1067320 | 0.76 | DRD1 (0.37) | ALOX15GFERADAM17DRD1ALDH1A1 | |
| SCHEMBL11065049 | 0.74 | DRD1 (0.56) | ALOX15GFERADAM17DRD1ALDH1A1 | |
| SCHEMBL457425 | 0.74 | GPR3 (0.37) | ALDH1A1MAPTKDM4EPOLBGAA | |
| SCHEMBL157708 | 0.73 | ALOX15 (0.50) | ALOX15GFERADAM17DRD1ALDH1A1 | |
| SCHEMBL1069758 | 0.72 | MAPT (0.37) | ALOX15GFERADAM17DRD1ALDH1A1 | |
| SCHEMBL1068000 | 0.72 | SCN5A (0.36) | ALOX15GFERADAM17DRD1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006886-A2 | AZOLE COMPOUNDS CARRYING A SULFUR SUBSTITUENT XIV | BASF SE (DE) | 2011-01-20 | — | — | WO | disclosed |
| WO-2010149758-A1 | ANTIFUNGAL 1, 2, 4-TRIAZOLYL DERIVATIVES | BASF SE (DE) | 2010-12-29 | — | — | WO | disclosed |