Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | LTC4S | Q16873 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LSS | P48449 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692514 | 0.85 | KMT2A (0.52) | TSHRLMNACYP1A2CYP2C19MEN1 | |
| SCHEMBL7848711 | 0.83 | LMNA (0.64) | TSHRLMNACYP1A2CYP2C19MEN1 | |
| SCHEMBL11525076 | 0.80 | MEN1 (0.42) | TSHRCYP2C19MEN1KMT2AALDH1A1 | |
| SCHEMBL10531019 | 0.80 | LTC4S (0.62) | TSHRLMNACYP1A2CYP2C19MEN1 | |
| SCHEMBL9313937 | 0.80 | KMT2A (0.52) | TSHRLMNACYP1A2CYP2C19MEN1 | |
| SCHEMBL9312633 | 0.78 | LMNA (0.64) | TSHRLMNACYP1A2CYP2C19MEN1 | |
| SCHEMBL10690638 | 0.78 | ACHE (0.53) | TSHRLMNACYP1A2CYP2C19MEN1 | |
| SCHEMBL9313237 | 0.78 | LMNA (0.48) | TSHRLMNACYP1A2CYP2C19MEN1 | |
| SCHEMBL4124832 | 0.77 | NPC1 (0.68) | TSHRLMNACYP1A2CYP2C19MEN1 | |
| SCHEMBL11399468 | 0.77 | AKR1C3 (0.54) | LMNAMEN1KMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4748148-A | Recording system utilizing phthalide derivatives as colorless chromogenic material | NEW OJI PAPER CO., LTD. (JP) | 1988-05-31 | — | — | US | disclosed |
| US-4641160-A | Recording system utilizing phthalide derivatives as colorless chromogenic material | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1987-02-03 | — | — | US | disclosed |
| EP-0062544-A1 | New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1982-10-13 | — | — | EP | disclosed |