Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11073178 | 0.92 | CA2 (0.43) | NPC1LMNAMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL11070254 | 0.90 | LMNA (0.45) | NPC1LMNAMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL11070344 | 0.87 | SMN1; SMN2 (0.39) | NPC1LMNAMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL10694504 | 0.87 | CA2 (0.51) | NPC1LMNAMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL11073531 | 0.84 | ALDH1A1 (0.43) | NPC1LMNAMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL9617635 | 0.82 | ALDH1A1 (0.41) | NPC1LMNAMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL30422274 | 0.82 | ALDH1A1 (0.41) | NPC1LMNAMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL10693011 | 0.82 | CDK1 (0.50) | MAPTSMN1; SMN2NPSR1ALDH1A1KDM4E | |
| SCHEMBL15010031 | 0.81 | ALDH1A1 (0.44) | NPC1LMNAMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11068781 | 0.80 | ATM (0.43) | MAPTALDH1A1KDM4ECYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4595768-A | 3-(substituted phenyl)phthalides | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-06-17 | — | — | US | claimed |
| US-4323700-A | OXIDIZING 3-PHENYL PHTHACIDE PERIVATIVES | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1982-04-06 | — | — | US | claimed |
| US-4732991-A | Substituted phthalides | HILTON DAVIS CHEMICAL CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4595768-A | 3-(substituted phenyl)phthalides | THE HILTON-DAVIS CHEMICAL CO. (US) | 1986-06-17 | — | — | US | disclosed |
| US-4443614-A | LEUCO DYES, PHTHALEIN DYES, INDICATORS | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1984-04-17 | — | — | US | disclosed |
| US-4439610-A | FROM AMINES AND PHTHALIDES, MULTISTAGE | KANZAKI PAPER MANUFACTURING COMPANY, LTD. (JP) | 1984-03-27 | — | — | US | disclosed |
| US-4323700-A | OXIDIZING 3-PHENYL PHTHACIDE PERIVATIVES | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4045458-A | FRIEDEL-CRAFTS CATALYSTS | KANZAKI PAPER MANUFACTURING CO., LTD. (JA) | 1977-08-30 | — | — | US | disclosed |