SCHEMBL10693011

SCHEMBL10693011

COc1ccc(C2OC(=O)c3cc(N(C)C)ccc32)cc1OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.50
CCNB1 P14635 1/20 0.50
GSK3A P49840 1/20 0.50
GSK3B P49841 1/20 0.50
CDK5 Q00535 1/20 0.50
CDK5R1 Q15078 1/20 0.50
GAA P10253 2/20 0.44
RAB9A P51151 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 2/20 0.42
PTAFR P25105 1/20 0.40
MAPK1 P28482 1/20 0.40
ACHE P22303 2/20 0.39
NR3C1 P04150 1/20 0.39
MAPT P10636 1/20 0.39
HPGD P15428 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NQO2 P16083 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10692371 0.91 PDE4A (0.45) CDK1CCNB1GSK3AGSK3BCDK5
SCHEMBL10692102 0.85 LMNA (0.44) RAB9AALDH1A1MAPK1NR3C1MAPT
SCHEMBL11073178 0.84 CA2 (0.43) GAANPSR1ALDH1A1KDM4ENR3C1
SCHEMBL339072 0.84 ALDH1A1 (0.47) GAAALDH1A1KDM4EMAPTHPGD
SCHEMBL10691577 0.82 NPC1 (0.50) GAANPSR1ALDH1A1KDM4ENR3C1
SCHEMBL10680094 0.80 ALDH1A1 (0.44) GAAALDH1A1KDM4EMAPTHPGD
SCHEMBL11281281 0.80 ALDH1A1 (0.44) GAAALDH1A1KDM4ENR3C1MAPT
SCHEMBL11070344 0.80 SMN1; SMN2 (0.39) GAANPSR1ALDH1A1KDM4EMAPK1
SCHEMBL10694504 0.80 CA2 (0.51) NPSR1ALDH1A1KDM4EMAPK1MAPT
SCHEMBL11063311 0.80 ALDH1A1 (0.58) GAARAB9ANPSR1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4595768-A 3-(substituted phenyl)phthalides THE HILTON-DAVIS CHEMICAL CO. (US) 1986-06-17 US claimed
US-4323700-A OXIDIZING 3-PHENYL PHTHACIDE PERIVATIVES KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1982-04-06 US claimed
EP-3134443-B1 LED PHOTOINITIATORS SUN CHEMICAL CORP (US) 2019-10-30 EP disclosed
US-9938232-B2 LED photoinitiators SUN CHEMICAL CORPORATION (US) 2018-04-10 US disclosed
EP-3134443-A1 LED PHOTOINITIATORS Sun Chemical Corporation (US) 2017-03-01 EP disclosed
US-20170044093-A1 LED PHOTOINITIATORS SUN CHEMICAL CORPORATION (US) 2017-02-16 US disclosed
WO-2015164208-A1 LED PHOTOINITIATORS SUN CHEMICAL CORPORATION (US) 2015-10-29 WO disclosed
US-4732991-A Substituted phthalides HILTON DAVIS CHEMICAL CO. (US) 1988-03-22 US disclosed
US-4595768-A 3-(substituted phenyl)phthalides THE HILTON-DAVIS CHEMICAL CO. (US) 1986-06-17 US disclosed
US-4443614-A LEUCO DYES, PHTHALEIN DYES, INDICATORS KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1984-04-17 US disclosed
US-4439610-A FROM AMINES AND PHTHALIDES, MULTISTAGE KANZAKI PAPER MANUFACTURING COMPANY, LTD. (JP) 1984-03-27 US disclosed
US-4323700-A OXIDIZING 3-PHENYL PHTHACIDE PERIVATIVES KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1982-04-06 US disclosed
US-4045458-A FRIEDEL-CRAFTS CATALYSTS KANZAKI PAPER MANUFACTURING CO., LTD. (JA) 1977-08-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170044093-A1 LED PHOTOINITIATORS CCNA1, CYBA, H1-0 CDK1 30/4885CCNB1 5/4885GSK3A 3708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.