Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 9/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11798204 | 0.88 | LMNA (0.52) | ALDH1A1HSD17B10PPARALMNAKDM4E | |
| SCHEMBL1959315 | 0.87 | ALDH1A1 (0.50) | ALDH1A1HSD17B10PPARALMNAKDM4E | |
| SCHEMBL8629181 | 0.75 | ALDH1A1 (0.44) | ALDH1A1HSD17B10PPARALMNAKDM4E | |
| SCHEMBL14583501 | 0.72 | ALDH1A1 (0.87) | ALDH1A1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL9749529 | 0.72 | ALDH1A1 (0.47) | ALDH1A1HSD17B10PPARALMNAKDM4E | |
| SCHEMBL9750226 | 0.70 | KDM4E (0.45) | ALDH1A1HSD17B10PPARALMNAKDM4E | |
| SCHEMBL9834413 | 0.69 | ALDH1A1 (0.61) | ALDH1A1PPARALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL9749075 | 0.69 | KDM4E (0.44) | ALDH1A1HSD17B10PPARALMNAKDM4E | |
| SCHEMBL5717590 | 0.67 | ALDH1A1 (1.00) | ALDH1A1HSD17B10LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL8857767 | 0.67 | ALDH1A1 (0.45) | ALDH1A1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| EP-0194572-A1 | Heterocyclic sulfides, process for their preparation and Medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-17 | — | — | EP | disclosed |