Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750226 | 0.81 | KDM4E (0.45) | KDM4ELMNAPPARAALDH1A1NPSR1 | |
| SCHEMBL14156190 | 0.81 | SMN1; SMN2 (0.53) | KDM4ELMNAPPARAALDH1A1NPSR1 | |
| SCHEMBL9749267 | 0.78 | SMN1; SMN2 (0.44) | LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL14156102 | 0.76 | GABRA5 (0.49) | KDM4ELMNAPPARAALDH1A1HSD17B10 | |
| SCHEMBL29285032 | 0.73 | HDAC3 (0.36) | KDM4ELMNAPPARAALDH1A1RXFP1 | |
| SCHEMBL24917646 | 0.72 | SHMT1 (0.37) | KDM4ELMNAPPARAALDH1A1RXFP1 | |
| SCHEMBL1565803 | 0.72 | HSD17B10 (0.46) | KDM4ELMNAALDH1A1HSD17B10SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL1758691 | 0.70 | HSD17B10 (0.44) | KDM4ELMNAALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL18099911 | 0.69 | PIK3CD (0.32) | KDM4ELMNAALDH1A1RXFP1 | |
| SCHEMBL10691578 | 0.69 | ALDH1A1 (0.63) | KDM4ELMNAPPARAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| EP-0194572-A1 | Heterocyclic sulfides, process for their preparation and Medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-17 | — | — | EP | disclosed |