Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.40 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14156190 | 0.83 | SMN1; SMN2 (0.53) | KDM4ELMNAL3MBTL1PPARAALDH1A1 | |
| SCHEMBL9749075 | 0.81 | KDM4E (0.44) | KDM4ELMNAPPARAALDH1A1CSNK2A2 | |
| SCHEMBL9749238 | 0.79 | HTT (0.46) | L3MBTL1PPARAALDH1A1PRKAG1PRKAA2 | |
| SCHEMBL14156102 | 0.78 | GABRA5 (0.49) | KDM4ELMNAPPARAALDH1A1HSD17B10 | |
| SCHEMBL3114211 | 0.76 | L3MBTL1 (0.50) | KDM4EL3MBTL1ALDH1A1PRKAG1PRKAA2 | |
| SCHEMBL9749240 | 0.76 | L3MBTL1 (0.41) | LMNAL3MBTL1ALDH1A1PRKAG1PRKAA2 | |
| SCHEMBL6825656 | 0.75 | L3MBTL1 (0.48) | KDM4EL3MBTL1ALDH1A1PRKAG1PRKAA2 | |
| SCHEMBL9481442 | 0.72 | L3MBTL1 (0.46) | KDM4EL3MBTL1ALDH1A1PRKAG1PRKAA2 | |
| SCHEMBL14805662 | 0.71 | L3MBTL1 (0.46) | KDM4EL3MBTL1ALDH1A1PRKAG1PRKAA2 | |
| SCHEMBL12964364 | 0.71 | PLA2G4A (0.46) | KDM4ELMNAL3MBTL1ALDH1A1PRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0194572-B1 | HETEROCYCLIC SULFIDES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| EP-0194572-A1 | Heterocyclic sulfides, process for their preparation and Medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-17 | — | — | EP | disclosed |